[BioSB] TintoFast Cytokeratin AE1/AE3 (AE1/AE3), MMab

[BioSB] TintoFast Cytokeratin AE1/AE3 (AE1/AE3), MMab

 

 

Catalog No.	Antibody Type	Dilution	Volume/QTY
BSB 3663	TintoFast Prediluted	Ready-To-Use	3.0 ml
BSB 3664	TintoFast Prediluted	Ready-To-Use	7.0 ml
BSB 3665	TintoFast Prediluted	Ready-To-Use	15.0 ml

 

 

Intended Use	For Mohs In Vitro Diagnostic Use
Summary and Explanation	Cytokeratins are intermediate-filament keratins found in the intracytoplasmic cytoskeleton of epithelial tissue. There are two types of cytokeratins: the low-weight, acidic Type I cytokeratins and the high-weight, basic or neutral Type II cytokeratins. Cytokeratins are usually found in pairs comprising a Type I cytokeratin and a Type II cytokeratin. Expression of these cytokeratins is frequently organ or tissue-specific. TintoFast Cytokeratin AE1/AE3 is well suited to distinguish Epithelial Carcinoma from Non-epithelial malignancies and is used to aid Epithelial Tumor classification.  This antibody has been used to characterize the source of various neoplasms and to study the distribution of keratin-containing cells in epithelia during normal development and during the development of epithelial neoplasms.  This antibody stains cytokeratins present in normal and abnormal human tissues. TintoFast Cytokeratin AE1/AE3 has shown high sensitivity and specificity in recognizing epithelial cells of neoplastic origin.
	Antibody Type	Mouse Monoclonal	Clone	AE1/AE3
	Isotype	IgG1	Reactivity	Paraffin, Frozen
	Localization	Cytoplasmic	Control	Skin, SCC, BCC
Presentation	Anti – Cytokeratin AE1/AE3 is a cocktail of mouse monoclonal antibodies derived from cell culture supernatant that is concentrated, dialyzed, filter sterilized and diluted in buffer pH 7.5, containing BSA and sodium azide as a preservative.