[Leading Biology] Phospho-PFKFB2-S483 pAb

[Leading Biology] Phospho-PFKFB2-S483 pAb

 

AMR01067N

 

Brand	Leading Biology	Catalog Number	AMR01067N
Product Type	Phosphorylated Antibodies	Field of Research	Endocrine & Metabolism>Carbohydrate metabolism

 

Product Overview	We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality Phospho-PFKFB2-S483 pAb.
Molecular Weight	Calculated MW: 54kDa/58kDa Observed MW: Refer to figures
Species Reactivity	Rabbit
Immunogen	A synthetic phosphorylated peptide around S483 of human PFKFB2 (NP_006203.2).
Cross Reactivity	Human,Mouse
Isotype	IgG
GeneID	5208
UniProt ID	O60825
Purity	Affinity purification
Storage & Stability	Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Storage Buffer	Buffer: PBS with 50% glycerol, pH7.3.
Applications	WB,IP
Dilution	WB 1:500 - 1:2000 IP 1:50 - 1:100
Product Description	The protein encoded by this gene is involved in both the synthesis and degradation of fructose-2,6-bisphosphate, a regulatory molecule that controls glycolysis in eukaryotes. The encoded protein has a 6-phosphofructo-2-kinase activity that catalyzes the synthesis of fructose-2,6-bisphosphate, and a fructose-2,6-biphosphatase activity that catalyzes the degradation of fructose-2,6-bisphosphate. This protein regulates fructose-2,6-bisphosphate levels in the heart, while a related enzyme encoded by a different gene regulates fructose-2,6-bisphosphate levels in the liver and muscle. This enzyme functions as a homodimer. Two transcript variants encoding two different isoforms have been found for this gene.
Synonyms	PFKFB2; PFK-2/FBPase-2; 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2