[Leading Biology] Recombinant Human TGFA Protein
PH0143E2
Recombinant Human TGFA Protein
Brand |
Leading Biology |
Catalog Number |
PH0143E2 |
Product Type |
Cytokine |
Field of Research |
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Nature |
Recombinant Protein |
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Expression Host |
E.coli |
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Species |
Human |
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AA Sequence |
P01135-1(Val40-Ala89) |
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Tags |
Tag-Free |
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Molecular Weight |
13KD |
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Form |
lyophilized |
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Purity |
Greater than 95% by SDS-PAGE |
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Storage & Stability |
-70°C |
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Storage Buffer |
0.2 μm filtered 50 mM Tris, 100 mM NaCl, pH 8.0 |
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Product Description |
Transforming growth factor alpha (TGF-α) is a protein that in humans is encoded by the TGFA gene. As a member of the epidermal growth factor (EGF) family, TGF-α is a mitogenic polypeptide. The protein becomes activated when binding to receptors capable of protein kinase activity for cellular signaling. TGF-α is a transforming growth factor that is a ligand for the epidermal growth factor receptor, which activates a signaling pathway for cell proliferation, differentiation and development. This protein may act as either a transmembrane-bound ligand or a soluble ligand. This gene has been associated with many types of cancers, and it may also be involved in some cases of cleft lip/palate. |
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Synonyms |
TGF-alpha Protein(Human) |
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