[Genomeme] Annexin A1
Cat. No.IHC512-100
Specifications
Clone
IHC512
Source
Mouse Monoclonal
Positive Control
Hairy Cell Leukemia
Dilution Range
1:50-1:200
Description
Annexin A1 (ANXA1) is a membrane protein that plays a role in innate and adaptive immunity by controlling the biosynthesis of inflammation, prostaglandins, and leukotriene mediators. This target is overexpressed in 97% of all samples from patients with with hairy cell leukemia, and is absent in other B-cell lymphomas. High ANXA1 expression is frequently associated with advanced stage esophageal and esophagogastric junction adenocarcinoma, and is also linked to advanced and metastatic disease states.
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