[Genomeme] B7-H3

[Genomeme] B7-H3

 

CAT. NO. IHC039-100

 

CLONE:
IHC039

HOST SPECIES:
Rabbit

CLONALITY:
Monoclonal

POSITIVE CONTROL:
Tonsil

INTENDED USE/REG. STATUS:
RUO

 

B7 homolog 3 (B7-H3), also known as CD276, belongs the B7 immunoglobulin superfamily of cell surface ligands that regulate T cell activation and immune responses. Soluble B7-H3 binds a putative receptor on activated T-cells that is distinct from CD28, CTLA-4, ICOS and PD-1. B7-H3 is expressed by antigen presenting cells, activated T cells, and a few normal tissues, including placenta and prostate. Expression of B7-H3 is also seen in several cancer types, such as prostate, breast, colon, lung, and gastric cancers.