[Genomeme] ATRX

[Genomeme] ATRX

 

 

CAT. NO. IHC703-100

 

CLONE:
IHC703

HOST SPECIES:
Mouse

CLONALITY:
Monoclonal

POSITIVE CONTROL:
Glioma

INTENDED USE/REG. STATUS:
RUO

 

ATRX is involved in the remodeling of the nucelosome structure, and facilitate the transcription and replication. ATRX loss occurs in grades II/III astrocytomas and glioblastomas and comes together with IDH1 mutations. Detection of ATRX with IHC acts a sensitive method to identify the mutations.