[Signalway Antibody - SAB] QK1 Rabbit mAb #52537
- Product Name
- QK1 Rabbit mAb
- Host Species
- Recombinant Rabbit
- Clonality
- Monoclonal antibody
- Clone No.
- S01-3F7
- Isotype
- Rabbit IgG
- Purification
- Affinity Purified
- Applications
- WB
- Species Reactivity
- Human,Mouse,Rat
- Immunogen Description
- A synthetic peptide of human QK1
- Conjugates
- Unconjugated
- Modification
- Unmodification
- Alternative Names
- Accession No.
- Swiss-Prot:Q96PU8
GeneID:9444 - Uniprot
- Q96PU8
- Gene ID
- 9444
- Calculated MW
- Calculated MW: 38 kDa; Observed MW: 38 kDa
- Concentration
- 0.3 mg/ml
- Formulation
- 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
- Storage
- Store at 4˚C short term. Aliquot and store at -20˚C long term. Avoid freeze/thaw cycles.
Swiss-Prot Acc.Q96PU8.RNA-binding protein that plays a central role in myelinization (PubMed:16641098). Binds to the 5'-NACUAAY-N(1,20)-UAAY-3' RNA core sequence. Regulates target mRNA stability (PubMed:23630077). In addition, acts by regulating pre-mRNA splicing, mRNA export and protein translation. Required to protect and promote stability of mRNAs such as MBP and CDKN1B. Regulator of oligodendrocyte differentiation and maturation in the brain that may play a role in myelin and oligodendrocyte dysfunction in schizophrenia (PubMed:16641098). Participates in mRNA transport by regulating the nuclear export of MBP mRNA. Also involved in regulation of mRNA splicing of MAG pre-mRNA. Acts as a translational repressor .
