[FenicsBio] Human TRPM6 Knockout A549 cell line

[FenicsBio]  Human TRPM6 Knockout A549 cell line

 

 

Catalog number

A549KO-19795

 

 

Gene symbol	TRPM6
Synonyms	CHAK2 HMGX HOMG HOMG1 HSH
Species	HUMAN
Gene ID	140803
Summary	This gene is predominantly expressed in the kidney and colon, and encodes a protein containing an ion channel domain and a protein kinase domain. It is crucial for magnesium homeostasis, and plays an essential role in epithelial magnesium transport and in the active magnesium absorption in the gut and kidney. Mutations in this gene are associated with hypomagnesemia with secondary hypocalcemia. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene. [provided by RefSeq, Apr 2010].

Knockout cell line information

Deliverables	One vial of gene knockout cells (1x10^6 cells) and one vial of control parental cells (1x10^6)
Parental cell line	A549
Genotype	TRPM6-/-
Validation	Sanger Sequencing
Mammalian selection	N/A
Biosafety level	2
Storage	Liquid nitrogen
Availability	approximately 12 weeks