[ImmuSmol] Kynureninic Acid/Quinolinic Acid ELISA pack (KYNA/QA ELISA pack)

[ImmuSmol] Kynureninic Acid/Quinolinic Acid ELISA pack (KYNA/QA ELISA pack)

 

 

 

 

 

​

 

Ref: ISE-0102

Sample type	Serum, Plasma
Kit capacity	2 x 96 tests
Sensitivity	LoD KYNA: 0.53 ng/ml LoD QA: 6 ng/ml
Range	KYNA: 1.40 - 74 ng/ml QA: 25 - 2000 ng/ml
Species reactivity	Reacts with all species

Through the degradation of L-Tryptophan, the Kynurenine pathway (KP) generates a series of catabolites collectively known as Kynurenines, which can exert immunomodulatory and/or neuroactive properties. Known to respectively harbor neuroprotective and neurotoxic functions, Kynurenic (KYNA) and Quinolinic (QA) acids are found to be dysregulated in several neuroinflammatory disorders including Parkinson and Alzheimer disease but also Amyotrophic Lateral Sclerosis and Multiple Sclerosis.

 

The two kits included in the pack are ready to use, optimized for the quantitation of Kynurenic Acid (KYNA) and Quinolinic Acid (QA) within serum and plasma samples. These easy-to-use competitive assays are well-suited for both small and large series of samples. Working with a 25-50µL sample volume, these assays enable pre-clinical and clinical sample testings.

​

​

​