[Creative Peptides] Triptorelin Pamoate

[Creative Peptides] Triptorelin Pamoate

 

CAT#

10-101-101

 

CAS No.

57773-63-4 (net), 124508-66-3 (pamoate salt)

 

Explanation

Triptorelin pamoate is a potent LHRH agonist. After a transient increase, continuous administration results in downregulation of LH and FSH levels followed by a suppression of ovarian and testicular steroid biosynthesis.

Synonyms/Alias

5-Oxo-L-prolyl-L-histidyl-L-tryptophyl-L-seryl-L-tyrosyl-D-tryptophyl-L-leucyl-L-arginyl-L-prolylglycine amide, 4,4'-methylenebis(3-hydroxy-2-naphthoate) (salt); Decapeptyl; Diphereline; Gonapeptyl; Luteinizing hormone-releasing factor (swine), 6-D-tryptophan-, 4,4'-methylenebis(3-hydroxy-2-naphthalenecarboxylate) (salt); Pamorelin; Trelstar; Trelstar depot; Trelstar LA; Triptorelin embonate; UNII-08AN7WA2G0

 

Molecular Formula

C64H82N18O13

 

M.W/Mr.

1744.96

 

Sequence

Pyr-His-Trp-Ser-Tyr-D-Trp-Leu-Arg-Pro-Gly-NH2

 

Labeling Target

Gonadotropin-releasing hormone (GNRH) Receptor

 

Application

Triptorelin pamoate is classified as a gonadotropin releasing hormone (GnRH) agonist. In adult men with advanced prostate cancer, triptorelin pamoate can be used to help lower testosterone levels, which can be beneficial in stopping or slowing the growth of abnormal prostate tissue.

 

Activity

Agonist

 

Areas of Interest

Cancer Research

Pituitary & Hypothalamic Hormones
Veterinary Medicine

 

Functions

Peptide binding

 

Disease

Advanced Prostatic Carcinoma