[Leading Biology] CD63 Polyclonal Antibody

[Leading Biology] CD63 Polyclonal Antibody

 

 

APR25697N

 

Brand	Leading Biology	Catalog Number	APR25697N
Product Type	Polyclonal Antibodies	Field of Research	Cardiovascular>Blood

Product Overview	We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality CD63 Polyclonal Antibody.
Molecular Weight	Calculated MW: 17kDa/23kDa/25kDa Observed MW: 53kDa
Species Reactivity	Rabbit
Immunogen	Recombinant fusion protein of human CD63 (NP_001771.1).
Cross Reactivity	Human,Mouse,Rat
Isotype	IgG
GeneID	967
UniProt ID	P08962
Purity	Affinity purification
Storage & Stability	Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Storage Buffer	Buffer: PBS with 50% glycerol, pH7.3.
Applications	WB,IHC,IF
Dilution	WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200
Product Description	The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. The encoded protein is a cell surface glycoprotein that is known to complex with integrins. It may function as a blood platelet activation marker. Deficiency of this protein is associated with Hermansky-Pudlak syndrome. Also this gene has been associated with tumor progression. Alternative splicing results in multiple transcript variants encoding different protein isoforms.
Synonyms	CD63; LAMP-3; ME491; MLA1; OMA81H; TSPAN30; CD63 antigen
Images	Western blot analysis of extracts of various cell lines, using CD63 Antibody. Immunohistochemistry of paraffin-embedded rat brain using CD63 antibody. Immunohistochemistry of paraffin-embedded mouse testis using CD63 antibody.