[TaiClone] Emicerfont
tcsc0003315
Specifications
Purity / Grade>98%
Solubility10 mM in DMSO
Smilessmiles
Misc Information
Alternative NamesGW876008
Observed Molecular W
Product Description
Emicerfont is a corticotropin-releasing factor type 1 (CRF1) receptor antagonist with an IC50 of 66 nM.
IC50 & Target: IC50: 66 nM (CRF1 receptor)[1]
In Vitro: Emicerfont is a corticotropin-releasing factor type 1 (CRF1) receptor antagonist with an IC50 of 66 nM[1].
In Vivo: At concentration of 10 mg/kg, Emicerfont reduces i.c.v. CRF-induced gerbil forepaw treading and marmoset defensive postures. Emicerfont also reduces rat pup ultrasonic vocalization at concentration of 30 mg/kg[1].
Information
CAS No786701-13-1
FormulaC22H24N6O2
Clinical Informationclinicalinformation
PathwayGPCR/G Protein
TargetCRFR
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