[Genomeme] Annexin A1

[Genomeme] Annexin A1

 

 

 

CAT. NO. IHC512-100

 

 

 

Specifications

 

 

CLONE:
IHC512

ISOTYPE:
IgG1

HOST SPECIES:
Mouse

CLONALITY:
Monoclonal

POSITIVE CONTROL:
Hairy Cell Leukemia

DILUTION RANGE:
1:200

INTENDED USE/REG. STATUS:
CE-IVD

Annexin A1 (ANXA1) is a membrane protein that plays a role in innate and adaptive immunity by controlling the biosynthesis of inflammation, prostaglandins, and leukotriene mediators. This target is overexpressed in 97% of all samples from patients with hairy cell leukemia, and is absent in other B-cell lymphomas. High ANXA1 expression is frequently associated with advanced stage esophageal and esophagogastric junction adenocarcinoma, and is also linked to advanced and metastatic disease states.