[Genomeme] CD57

[Genomeme] CD57

 

 

 

CAT. NO. 

IHC539-100

 

 

Specifications

 

CLONE:
IHC539

ISOTYPE:
IgM

HOST SPECIES:
Mouse

CLONALITY:
Monoclonal

POSITIVE CONTROL:
Tonsil

DILUTION RANGE:
1:200

INTENDED USE/REG. STATUS:
CE-IVD

 

 

Description

 

 

Cluster of Differentiation 57 (CD57), also known as NK-1, is an antigen detectable in natural killer cells, some T-lymphocytes and normal peripheral blood mononuclear cells, myeloid cells, and a variety of polypeptides, lipids, and chondroitin sulfate proteoglycans. CD57 is indicated as a marker for tumours of neuroendocrine origin, including pheochromocytomas, paragangliomas, medulloblastomas, and carcinoid tumour, as well as various neural tumours including neuromas, neurofibromas, schwannomas, and granular cell tumours. CD57 is also detectable in ganglioneuroma and prostate carcinoma. Anti-CD57 is used to distinguish nodular lymphocyte-predominant Hodgkin’s lymphoma from T-cell/histiocyte-rich large B-cell lymphoma, nodular sclerosis Hodgkin’s disease, and follicular lymphoma.