본문 바로가기
RuixiBio

[RuixiBio] PLGA-PEG-COOH

by 휴바이오랩(Hubiolab) 2022. 9. 21.

[RuixiBio] PLGA-PEG-COOH

 

R-PL1004

 

 

MW of PEG 1000 Dalton,2000 Dalton,3400 Dalton,5000 Dalton
MW of PLGA As your request
LA:GA 90:10, 85:15, 75:25, 70:30, 50:50
PDI by GPC <1.5
Substitution by NMR COOH>90%
Reactive group Amine
Solubility Dichloromethane, Chloroform
Storage -20℃ protected from light and moisture
Transportation 4-25℃ temperature for up to 2 weeks
Stability 1 year
Literature author Yougan Chena , Yuanyuan Denga , Chenyao Zhub , Congming Xiang
Document name Anti prostate cancer therapy: Aptamer-functionalized, curcumin and cabazitaxel co-delivered, tumor targeted lipid-polymer hybrid nanoparticles

PLGA-PEG-COOH, Poly(L-lactide-co-glycolide)-Polyethyleneglycol-carboxyl is a biodegradable functional amphiphilic block copolymer fordrug delivery. PLGA-PEG-COOH can conjugate with peptides, antibodies, proteinsand others which contain amine groups on the surface.