[Creative Peptides] Acetylcysteine Ph. Eur.

[Creative Peptides] Acetylcysteine Ph. Eur.

 

CAT#

10-101-106

 

CAS No.

616-91-1

 

Explanation

Acetylcysteine is also known as N-acetylcysteine or N-acetyl-L-cysteine or NAC. It is the N-acetyl derivative of cysteine. NAC is essentially a prodrug that is converted to cysteine (in the intestine by the enzyme aminoacylase 1) and absorbed in the intestine into the blood stream. Cysteine is a key constituent to glutathione and hence administration of acetylcysteine replenishes glutathione stores. Acetylcysteine can also be used as a general antioxidant which can help mitigate symptoms for a variety of diseases exacerbated by reactive oxygen species (ROS).

Synonyms/Alias

N-Acetyl-L-cysteine; NAC; L-α-Acetamido-β-mercaptopropionic acid; NSC-111180

Chemical Formula

C5H9NO3S

Molecular Formula

C5H9NO3S

M.W/Mr.

163.2

Sequence

N-Acetyl-L-cysteine

Labeling Target

Glutathione synthetase; Cystine/glutamate transporter

Application

Acute and chronic bronchitis, laryngitis, tracheitis or sinusitisPulmonary complications of cystic fibrosisParacetamol overdose
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Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Activity

Stimulator; Activator

Areas of Interest

Neurological Disease

Functions

Metallopeptidase activity;
Cystine:glutamate antiporter activity

Disease

Bronchiectasis; Amyloidosis; Bronchitis; Poisoning by acetaminophen; Cystic fibrosis of the lung