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BioSB

[BioSB] CD20 – MMab

by 휴바이오랩(Hubiolab) 2020. 9. 1.

[BioSB] CD20 – MMab

 

Catalog No. Antibody Type Dilution Volume/QTY
BSB 5190 Prediluted Ready-To-Use 3.0 ml
BSB 5191 Prediluted Ready-To-Use 7.0 ml
BSB 5192 Prediluted Ready-To-Use 15.0 ml
BSB 5193 Concentrated 1:250-1:1000 0.1 ml
BSB 5194 Concentrated 1:250-1:1000 0.5 ml
BSB 5195 Concentrated 1:250-1:1000 1.0 ml
BSB 5196 Control Slides 5
Intended Use For In Vitro Diagnostic Use
Summary and Explanation

CD20 is a transmembrane, non-glycosylated protein expressed on B-cell precursors and mature B-cells, but lost following differentiation into plasma cells. This antibody does not cross-react with non-hematopoietic neoplasms. CD20 (B-cell Pan) reacts with a membrane antigen present in B-cells.

CD20 antibody strongly recognizes Reed-Sternberg cells predominant in Hodgkin’s disease. Since no staining of histiocytes or plasma cells has been observed and CD20 antibody has not been detected in T-cell malignancies, it is a very strong marker of B-cell Lymphomas. B-cell Panmarker recognizes a formalin-resistant intracytoplasmic antigen.

Antibody Type Mouse Monoclonal Clone L26
Isotype IgG2a/K Reactivity Paraffin, Frozen
Localization Membranous Control Tonsil, Lymph Node
Presentation CD20 is a mouse monoclonal antibody derived from cell culture supernatant that is concentrated, dialyzed, filter sterilized and diluted in buffer pH 7.5, containing BSA and sodium azide as a preservative.

 

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